Wednesday, December 27, 2006

Space telescope to hunt planets

Artist's concept: Corot

The French-led Corot mission has taken off from Kazakhstan on a quest to find planets, not much bigger than Earth, outside our Solar System.

The mission is expected to provide a better understanding of planets smaller than Saturn, of which only a small number of examples are known so far.

The vast majority of the more than 200 extrasolar planets found to date have been detected from the ground by watching for the slight gravitational tug they exert on their parent stars, called the radial velocity technique.

The space telescope will monitor about 120,000 stars for tiny dips in brightness that result from planets passing across their faces.

The mission is capable of detecting tiny drops in light of only 300 parts per million, which is good enough to detect planets as small as two or three times the size of Earth.

The COROT mission is led by France's Centre National d'Etudes Spatiales (CNES) with participation from the European Space Agency (ESA). It will be put in a circular orbit 900 kilometres above Earth.

COROT will start its scientific observing campaign around the end of January 2007, after mission managers have tested its instruments to make sure everything is working properly. The entire mission is scheduled to last 2.5 years.

The multinational mission will also study the stars directly to uncover more about their interior behaviour.

Corot blasted off from the Baikonur Cosmodrome at 1423 GMT, carried into a polar orbit on a Soyuz-2-1b vehicle.

A European Space Agency (Esa) spokeswoman said the take-off had gone smoothly.

However, officials would not know until later whether the satellite had separated from its launcher correctly, she said.

From its vantage point 827km (514 miles) above the Earth, Corot will survey star fields for approximately 2.5 years.

The French space agency, Cnes, is working with six international partners: Esa, Austria, Spain, Germany, Belgium and Brazil.

'Chance' observation

Ian Roxburgh, professor of astronomy at Queen Mary, University of London, UK, is the Esa scientist on the mission.

"The exciting part of this mission is to look, or to try to find, planets that are similar to the Earth," he told the BBC.

Artist's concept: Planet crosses in front of star (Esa)
Finding a transit will involve a bit luck
"That is, they'll be somewhat bigger than the Earth, but they'll be made of rocky material able to sustain an atmosphere, and probably provide the sort of environment in which life could form.

"And of course subsequently, many years downstream, we will have more sophisticated measurements, instruments that will look for signatures of life. But at this stage, we need to understand how often there are planets like the Earth around other stars."

Corot will monitor the brightness of stars, looking for the slight drop in light caused by the transit of a planet.

This is a rare event - it relies on the chance alignment of the star and the planet with Earth. As a consequence, Corot must keep an eye on more than 100,000 stars.

Star tremors

With Corot, astronomers expect to find between 10 and 40 rocky objects slightly larger than Earth, together with tens of new gas giants similar to our Jupiter, in each star field they observe.

Every 150 days, Corot will move to a new field and begin observing again.

Its first target field is towards the centre of our galaxy, the Milky Way. Its next will be in the direction of the constellation Orion.

Corot's instrumentation is also designed to detect the subtle variation in a star's light caused by sound waves rippling across the surface. These waves are the equivalent of seismic waves on the Earth.

By studying these "starquakes", astronomers can gain a detailed insight into the internal conditions of the star.

Corot stands for "COnvection ROtation and planetary Transits".

The satellite is the first of a number of spacecraft that will hunt and study distant planets over the next few years.

Corot satellite (BBC)
1. 4CCD camera and electronics: Captures and analyses starlight
2. Baffle: Works to shield the telescope from extraneous light
3. Telescope: A 30cm mirror; it views the star fields
4. Proteus platform: Contains communication equipment, temperature controls and direction controls
5. Solar panel: Uses the Sun's radiation to power the satellite

From New Scientist, 27th December 2006 and BBC

A man who believes in Darwin as fervently as he hates God by Rod Liddle in The Spectator

I've highlighted in bold The Spectator article.

For those who don't feel like reading another hit piece, here's a quick quote from below to get the gist of it:


"Like all scientific theories, Darwinism will be amended — perhaps beyond recognition. Perhaps it will be discarded entirely. Either way, disavowing a divine being because it doesn't quite fit in with another here-today-gone-tomorrow theory seems a tad peremptory."

I sure hope the "here-today-gone-tomorrow theory" of gravity doesn't get any ideas. -Josh.

Reposted from:
http://www.spectator.co.uk





In the downstairs loo of Richard Dawkins's house in Oxford there's a framed award from the Royal Society; to remind visitors, or maybe Richard himself, that here lives a man of some purpose, some gravitas and intellectual clout. The Faraday prize is given to those who communicate science with brilliance and verve to the scientifically ignorant, thick general public. Richard has done a lot of that, ever since The Selfish Gene in 1976. It is his job these days; he holds the Simonyi chair in the public understanding of science at Oxford University. His latest wife, the actress Lalla Ward, has done her bit too, helping out various bereft timelords in Dr Who.

Richard himself is a bit of a timelord, if you like. A scientist forever battling an intractable foe — the daleks of religion. He is probably more famous these days for kicking God around than for the hard science of his earlier work (a fact he accepts, with some misgivings); he is our most belligerent and brilliant atheist. Show him a deity — Jehovah, Allah, Sat Guru, whoever — and he will stand up straight and nut it right between the eyes. He rarely yields, as I discovered when I interviewed him for Channel 4.

His latest book does all this and more. It is the (surprise) publishing success of the year and easily outsells those awful football autobiographies (170,660 so far). It is a book of rhetoric rather than science. The God Delusion is, like all the best books, riven with beguiling contradictions, full of interesting holes into which one can clamber and find oneself instantly transported to an alternative universe. It is Dawkins's broadside against God and those who are stupid enough to believe in him, or her, or it. A book against belief written with the fervour of one who believes utterly in non-belief. A book which insists that science must be a humble undertaking but which — driven by the logic of his argument — contains Dawkins's own abbrievated version of the Ten Commandments (for which thanks, mate). A book that, for a disinterested non-believer, shows a simple and touching faith in the scientific creed of Darwinism — which theory, only 147 years after its inception, is already looking rather flawed and careworn. And finally, as a neat little irony, a book that will trouser its author an enormous sackload of dosh, not because it is beautifully written and at times exquisitely argued, but because it is about that thing which the author believes must be banished — God.

The author is, as ever, affable, eloquent and charming. He settles into his armchair and immediately tells me, to my surprise, about the religious renewal he experienced when he was 14.

'I think it was Elvis. I mean, I should have known better because of course practically all Americans of that class are religious maniacs. But when I discovered that Elvis was religious I went back on to religion for a bit.'

It didn't last long; the man who gave the world 'Heartbreak Hotel' was soon replaced, in Richard's canon, by the man who gave us The Origin of Species. If Elvis rocked, Darwin rocked more. He rocks still, apparently. And thence there devolved along the years an insuperable belief in atheism.

'There seems to be a tension,' I venture, 'between what I suspect you believe — that there is no God — and what science will allow you to say: that it's extremely improbable that there is a God.'

'Right. I don't think you can disprove God. But I don't think you can disprove God as you can't disprove fairies and unicorns. It's a kind of scientific purism that makes me say I can't be an absolute 100 per cent atheist.'

'But, to read your book, you are 100 per cent, aren't you?'

'No. Some of my friends and colleagues would say that [for them] it's 100 per cent.'

Well, I counter, having read the book: it's 100 per cent for you, too; it burns through on every page. Otherwise the acres of rhetoric would have been displaced by pure, disinterested science.

'I think there is some truth in that. I think there are times when one has to resort to rhetoric. For a lot of people, religion is a question of feeling rather than rationality.'

But rhetoric is a device which must necessarily be in opposition to scientific discourse; in other words, Dawkins appropriates the tools of the believer when he feels that it is expedient to do so — and hang the science. But still, let's move on. By far the weakest part of The God Delusion is when Dawkins attempts to explain why atheistic regimes have far outdone religious regimes in their murderousness, their inhumanity. I asked Dawkins when he would leave the god- botherers alone, and he responded by saying, 'When they leave the rest of the world alone. When they leave children alone, stop fighting each other and endangering the rest of us.' Which is fair enough, but the record of those regimes which presciently forsook religion is far, far worse.

'Oh,' he says. 'I think that it is incidental that Stalin was an atheist. I don't think that Hitler was. Stalin did his deeds in the name of a kind of Marxism, and you can argue as to whether that's a religion or not.'

Isn't that the point, I suggest. That with one set of values removed, another will always fill its place? That if you remove religion, there is a gap which will always be filled — and usually by something worse than belief in a deity? Are we ever worse than when we feel ourselves to be unconstrained masters of our domain, answerable to nobody but ourselves?

'I agree with you that I have not sufficiently explained that. This gap, this absence — it could be a psychological weakness of the human mind. I did have one chapter at the end, but I think I didn't do it justice, from your point of view. If I were to, then I wouldn't have any trouble filling it — it might be science, it might be human love. Relationships, something like that.'

Relationships indeed. Richard has handily provided a new bunch of commandments to replace those which Moses handed down to the rest of us. But they are terribly ephemeral things, unintentionally hilarious — the sort of stuff that might be dreamed up by Polly Toynbee after someone had slipped an ecstasy tablet in her San Pellegrino after a long day in the Guardian offices. 'Have an enjoyable sexual relationship with someone of either gender but try not to hurt anyone while doing so' — that sort of thing. They have no resonance, not the slightest suggestion that they might outlast even our current generation, never mind provide us with a template for 2,000 years. 'I'm astonished you think it a good thing, longevity,' Dawkins counters, 'You say that my commandments are here today and gone tomorrow — but that's a good thing and that's one of the points I am trying to make. That there is a steadily shifting moral zeitgeist.'

But all this leaves you with a sort of damp and most unconvincing historical relativism. By Dawkins's argument, the moral imperatives of 500 years ago were, de facto, right then — and wrong now. In the end, it leaves you without a real sense of right and wrong, merely a constantly shifting plane — and thus open to the malefactions of a Hitler or a Stalin or a Mao or a Pol Pot. But of course, as I concede to Dawkins, the simple fact that Christianity has given us a moral code which has, to an extent, lasted 2,000 years is no reason to believe in a divinity. It is, though, a very valid reason to doubt ourselves — as the historical evidence would attest.

Which brings me to the difficult stuff — and Darwinism. It is a creed to which Dawkins cleaves with the fervour of the fundamentalist, the true believer. And it is the real chink in his armour. For example, because Darwin showed us that life forms progress from the simple to the complex over hundreds of thousands of years of gradual modification, it therefore follows (according to Dawkins) that there cannot have been a divine being present before the amoebae swam in those soupy oceans at Earth's toddler stage — because he would have had to be more complex than those organisms which followed him. And that doesn't fit with the theory. But what if the theory, in its entirety, doesn't hold — as Dawkins concedes might be possible? Even now, a century and a half after Darwin wrote The Origin of Species, the notion of gradual, cumulative change in every case is being challenged (most recently by the evo-devo school, which believes that sudden change can occur within species within a single generation). Like all scientific theories, Darwinism will be amended — perhaps beyond recognition. Perhaps it will be discarded entirely. Either way, disavowing a divine being because it doesn't quite fit in with another here-today-gone-tomorrow theory seems a tad peremptory. The question Dawkins can never satisfactorily answer is: what if Darwin was wrong? And yet, as a scientist, he must be aware that the likelihood is that Darwin was wrong here or there. In which case, where does that leave his philosophical argument?

And then there is this. For Richard Dawkins, the human being is a creature propelled by the blind impetus of his or her genes. Everything we do is, at root, guided by a cold mechanism designed to propagate the survival of these incalculably minute and ruthless constituents. There is nothing more. And yet Dawkins insists that as human beings we might uniquely overcome this mechanism. Why should we, alone among animals, be able to do so, to defy our genes? And how?

'I mean that it is the selfish gene, not the selfish individual,' Dawkins says.

Well, yes, sure; we talk about reciprocal altruism for a time. Clearly, though, Dawkins means that we can progress beyond even that. So what was it that gave us the ability mysteriously to overcome this implacable mechanism?

'Because we've got very big brains. I mean ...no other animal practises contraception, for example.'

'But,' I say to him, 'there is no reason why the complexity and size of our brains should lead us to do something which is precisely what our genes do not wish us to do, is there?' It would surely be the reverse: it is perfectly counter-Darwinian.

'Yes. But it happens to be true. Darwinian selection couldn't possibly ever have favoured contraception. That's simply a demonstration that it's possible to decide to do other noble things, like being nice....' Does that sound very scientific to you? It doesn't to me. It sounds horribly like a devout believer — a believer in non-belief, except when it comes to Darwinism — rather ineffectually attempting to dig himself out of a hole.

At the end, as we sip our coffee in this agreeable secular house, I ask Richard Dawkins if he has ever had a religious experience, i.e., something more profound than signing up to God because Elvis had done so before. 'No,' he says.

'What would convince you?'

He looks askance for a moment. 'Of a supernatural being?'

'Yep.'

'Well.' He has a think. 'I suppose a large-scale miracle which could not have been engineered by a conjuror. But I, um, find it hard to imagine exactly what that might be,' he concludes.

The question, I suspect, has never even occurred to him. It is one of those possibilities to which he is not — being human and fallible, and thus wedded to a certain train of thought and resistant to being diverged from it — wholly open.

Richard Dawkins's Commandments

1. Enjoy your own sex life (so long as it damages nobody else) and leave others to enjoy theirs in private whatever their inclinations, which are none of your business.

2. Do not discriminate or oppress on the basis of sex, race or (as far as possible) species.

3. Do not indoctrinate your children. Teach them how to think for themselves, how to evaluate science, and how to disagree with you.

4. Value the future of things on a timescale longer than your own.

The Trouble With Atheism is being shown on Channel 4 on 18 December.

*****************
Here are a few of the comments:

13. Comment #11837 by Noodly on December 7, 2006 at 3:26 pm

 avatarIt's funny how Liddle emphasises that science will have to modify evolution theories, discarding and adding bits as new information comes to light - WELL THAT'S THE WHOLE BLOODY POINT OF SCIENCE. KNOWLEDGE EVOLVES.

He can't find anything to discredit Dawkin's destruction of God so he tries to make him out as some sort of Darwinian fundamentalist. Dawkins has stated that he would the first to dump Darwin and/or admit to God's existence if new evidence was overwhelming.

No one's forcing anyone to change their view on God. The Zeitgeist is encouraging frank exchanges of views rather than sweeping them under the carpet in order to avoid "offense".

The tide is turning.


43. Comment #12082 by rmgantt on December 10, 2006 at 9:00 am

Darwinism flawed and careworn? Little doesn't understand that the point of scientific theories is to under go change and metamorphosis as new evidence is discovered which refines the theory. These changes do not suggest that the theory is flawed or careworn, rather, that it is more and more relavent, becoming more polished over time.


46. Comment #12474 by Umslopogaas on December 12, 2006 at 5:35 am

Liddle says that "By far the weakest part of the God Delusion is where Dawkins attempts to explain why atheistic regimes have far outdone religious regimes in their murderousness, their imhumanity". Whether Dawkins's argument is weak or not is totally irrelevant to whether God exists. Even if every religious regime throughout history were all sweetness and light and every atheistic state brutal and fascistic, it makes not a jot of difference to nor throws any light on the argument. God either exists or does not and what authority, secular or divine, administrations appeal to when justifying their actions has no bearing on the issue.

47. Comment #13114 by Michael on December 15, 2006 at 3:26 pm

I was so incenced by Liddles article that I sent the following repost to the Spectator. Not suprisingly they haven't printed it! Seeing Liddles contribution this week I can see that he really is the Tory party at prayer.

Sir.
Why is it that critics of Dawkins and his recent book, imbued with faith, attack by innuendo but without evidence. They attack the messenger and not the message. Rod Liddle's interview is one such and it starts in the first paragraph; "his latest wife, the actress Lalla Ward……." Is he gratuitously questioning Dawkins' domestic stability and might the pot be calling the kettle black? In any event, domestic state does not impinge on the thesis that religions are not based on evidence.

Liddle goes on to criticize The God Delusion as a book of rhetoric and not science. He is wrong in that there is plenty of science, but religions are based on rhetoric and so it is hardly surprising that Dawkins uses religious rhetoric for some arguments.

Liddle makes another egregious error in suggesting that Darwin's theory of evolution is 'flawed and careworn'. It is not. For professionals it remains as fresh and coherent as the day it was written. There is so much evidence in support of the theory that it is now as much scientific fact as Newtonian physics. Ever more research data serves to reinforce the original concept, but refine the detail, much as physics has developed from Newton through Einstein to Quantum. The very nature of science is to progress, refine, refute, develop and enlarge our understanding of the world and space. If Liddle doubts the mechanics of evolution, he might like to consider why Northern races of humans have lost skin pigment and why human faces are so different across the world. Our current species of Homo sapiens migrated out of Africa as recently as some 40,000 years ago and yet so much has changed so quickly. Why? He might also like to consider how long it might have taken for humans to have actually speciated again; something happily prevented by widespread travel and migration these last few hundred years.

Liddle goes on to say that Dawkins clings to the creed of Darwinism like the true believer. Wrong again. Dawkins merely adheres to evidence, for which there is much in biological science but none for religions. The latter alone depends on faith and creeds.

'Relationships indeed' sneers Liddle when Dawkins discusses the changing Zeitgeist as if religions haven't evolved over time. How many different sects of Christianity and Islam are there today? All catering for the imperatives of their various adherents, as wishes have changed over 2000 years. Yet all professing the absolute truth. Religions are themselves a product of the Zeitgeist and move with it.

Liddle repeats the hackneyed contention that leaders without faith have propounded the most and greatest evils. Oh yes! Where is the evidence? Stalin yes, but nearly all the rest have been religious adherents including Hitler and Genghis Khan. Even Blair and Bush, devout Christians, deliberately deceived their public when invading Iraq. And isn't the indoctrination of our children with elaborate fairy stories and great guilt, serious ongoing abuse? There is no evidence that morality stems from religion but has indeed been incorporated into religion. Morality derives from biological pragmatism and simpler variants are common among many social species. It also predates the present 'great religions'.

One might ask why religions are so pervasive despite being based on so little evidence. It is probably because it provides such a powerful aid for the alpha males ruling their people. It overrides the alpha male and cannot be dismissed with the same ease as deposing the leader. It invests the leader with supernatural authority. It is also a useful means of making large groups of people cohesive. Clan or tribe size has clear advantage in defending territory against neighbours. Religion then becomes very much part of the clan scent, to use an animal analogy. A possible example of group selection and not merely a by-product of our long adolescence.

Liddle ends his piece with the 'killer question'. 'What would make you believe in God?' The question, Liddle suspects, has never occurred to Dawkins. Well, if he had followed some of Dawkins many public appearances he would realise that it is a recurrent question, which always draws a variant of the same answer. The only possible answer. Evidence. Sound objective evidence and Dawkins would change his mind as any good scientist

Scan could spot early Alzheimer's


Alzheimer's tissue. Picture: UCLA
The brown amyloid plaques are linked to Alzheimer's. Pic: UCLA
Patients with the earliest symptoms of Alzheimer's disease could be diagnosed using an advanced scanning technique.

A team at the University of California, Los Angeles, says it has found a way to highlight distinctive brain changes linked to Alzheimer's.

Although the disease can be diagnosed by assessing mental decline, physical changes within the brain can usually be confirmed only by a post-mortem.

The study appears in the New England Journal of Medicine.

The UCLA team says its technique might be effective long before disabling symptoms emerge.

This might allow drugs and other therapies to be employed at an earlier stage to slow the progression of the illness, although no cure for Alzheimer's exists.

Marking the spot

Alzheimer's disease is strongly linked to the appearance of abnormal areas called 'amyloid plaques' and 'tangles', although the precise role of these is not fully understood.

However, they do not show up using conventional MRI or CT scanning, and are visible only during an autopsy.

This imaging technology may also allow us to test novel drug therapies and manage disease progression over time
Dr Gary Small, UCLA

The UCLA team has invented a chemical which not only shows up on scans, but will bind to plaques and tangles.

Using 'Positron Emitting Tomography' (PET), another type of scanner, damaged areas show up clearly.

However, more evidence was needed that the scan results could be linked to the progression of other symptoms in the disease.

More than 80 people volunteered for the research, some of them healthy, some with 'mild cognitive impairments' such as memory loss, and 25 of whom had received a diagnosis of Alzheimer's because their symptoms were more advanced.

After being injected with the chemical, they were scanned to see if there were any differences between the groups.

The levels of the chemical appearing on the scans were much higher among the Alzheimer's patients compared with the others, and the technique also highlighted more subtle differences between the healthy volunteers and those with the mild symptoms.

In severely affected patients, concentrations of the chemical appeared highest in parts of the brain usually affected by Alzheimer's plaques and tangles.

The researchers then waited two years before scanning the same patients again - and found that those who had worsened during that period, showed clear increases in the levels of the chemical in their brain.

Results confirmed

In addition, when one of the trial patients died 14 months after the first scan, an autopsy confirmed the appearance of amyloid plaques and tangles in exactly the locations the scan had suggested.

The ability to diagnose at the earliest possible stage is of huge importance to people with Alzheimer's disease
Professor Clive Ballard, Alzheimer's Society
Dr Gary Small, who led the study, said: "This suggests that we may now have a new diagnostic tool for detecting pre-Alzheimer's conditions to help us identify those at risk, perhaps years before symptoms become obvious.

"This imaging technology may also allow us to test novel drug therapies and manage disease progression over time, possibly protecting the brain before damage occurs."

Professor Dorothy Auer, from Nottingham University, is also working to develop techniques to spot the telltale amyloid plaques using conventional scanners.

She told BBC News Online that any method which could highlight both tangles and plaques was 'exciting'.

"It would be extremely useful to have an accurate method of diagnosis for Alzheimer's disease - however, it is early days for these techniques."

Professor Clive Ballard, director of research at the Alzheimer's Society, said: "This new research could prove significant in the early diagnosis of Alzheimer's disease.

"The ability to diagnose at the earliest possible stage is of huge importance to people with Alzheimer's disease."

Statins block synthesis of Coenzyme Q10 and ATP production

As James Kingsland wrote in his article on statins, "blocking of HMG CoA reductase inhibits the production of many other molecules beside cholesterol".

Statins also block the synthesis of coenzyme Q10. In a 30-day study using atorvastatin blood levels of CoQ10 were halved (Archives of Neurology, vol 61, p 889). This block was neither mentioned in Kingsland's article nor considered by the Clinical Trials Service Unit (CTSU) - whose report is at http://www.ctsu.ox.ac.uk/~hps/statin_paper.shtml - although three other antioxidants were included in the trial. CoQ10, an antioxidant, is a key component of the oxygen-driven electron transport system in mitochondria, and this system plays a large part in ATP (adenosine triphosphate) synthesis in all our cells except red blood cells.

ATP is the crucial energy source of heart and brain and its loss is ultimately responsible for deaths following myocardial infarction or ischaemic stroke.

The potential for a fall in CoQ10 was recognised long before these reports. A major drug company was granted a patent for combined CoQ10/statin therapy in 1990 - see US Patent 4933165 at www.uspto.gov. One can only speculate as to the reason why this was never taken up.

The reported side effects of statins in muscle and cognitive function could be the result of blocking CoQ10 synthesis.

Finally, the CTSU studied people who already had a substantial risk of death within five years. As your article said, the meta-analysis cranked out significant positive results, but there was no dramatic effect on outcome, even in these patients, at the doses which have to be used to minimise side effects.

So prescribing statins for almost everyone - or putting them in the tap water, as one madcap enthusiast in the UK suggests - could benefit only those who profit from selling them. If "you bet your life on" taking statins, you should insist on a coenzyme Q10 supplement. As the article suggests, there are alternatives such as a healthy lifestyle, boosting vitamin D and perhaps - for those whose can take it - low-dose aspirin.

Falmouth, Cornwall, UK

From issue 2576 of New Scientist magazine, 04 November 2006, page 25